There is no treatment for the progressive neurodegenerative lysosomal storage disorder mucopolysaccharidosis type IIIA (MPS IIIA). which occurs due to a deficiency of functional N-sulfoglucosamine sulfohydrolase (SGSH). with subsequent accumulation of partially-degraded heparan sulfate and secondarily-stored compounds including GM2 and GM3 gangliosides and unesterified cholesterol. Th... https://www.popularfilm.blog/